2C-B 101 - Interactive Course

Let's learn about

2C-B

4-bromo-2,5-dimethoxyphenethylamine

AKA Nexus, Venus, Bees, Erox

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What is it?

2C-B is a

psychedelic entactogen

A synthetic compound in the phenethylamine family - the same family as mescaline. It shifts perception, mood, and the body: visuals and color alongside a warm, emotionally open, sociable headspace.

Comes as powder or pressed pillsTaken usually swallowed; snorting is far harsher and comes on faster

1974Created

'70sTherapy

1985Clubs

1995Banned

TodayStudied

What does the
research show?

Tap each card to flip and reveal a finding

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Eased anger, raised emotional opennessGonzalez et al., 2015

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Gentler mood profile than psilocybinMallaroni et al., 2023

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Comparable visuals, better toleratedMallaroni et al., 2023

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A therapy candidate - but no completed trialsEarly research

2C-B is one of the least-studied psychedelics. Most of what we know comes from small, observational studies - not large clinical trials.

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How it unfolds

Tap through the journey

Before

Set & dose

Weigh it on a milligram scale and set your intention. A few milligrams changes everything.

Visuals

Warmth

Body load

Tap through to the end to continue

Quick check

You've got loose powder sold as 2C-B and no scale. What's safest?

Harm reduction

Tap each to check it off

✓

Use a milligram scale - never eyeball a 2C-B dose

✓

Test it first - what's sold as 2C-B is often something else

✓

Start low and go slow - a few milligrams changes everything

✓

Avoid mixing - lithium, tramadol, and MAOIs are especially dangerous. Check any prescription meds before combining

✓

Mind set & setting, and keep a trusted, sober person nearby

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What are the risks?

Very dose-sensitive - a few milligrams can overwhelm you

Nausea, especially on the come-up

Raised heart rate and blood pressure

Muscle tension, teeth grinding, and sweating

Anxiety, panic, or paranoia - more likely at higher doses

Higher risk with a personal or family history of psychosis or mood disorders

Tap to reveal the next risk

2C-B isn't considered physically addictive, but what's sold as "2C-B" is often mislabeled - and a hard experience can stay with you. Dose, set, and setting all matter.

Where it stands

The law - and what's really in the bag

ISchedule I in the U.S. since 1995 - and controlled in most countries

1974First made by chemist Alexander Shulgin - legal for its first two decades

Tusi"Tusi" / "pink cocaine" is usually NOT 2C-B - often an MDMA-ketamine mix. Always test.

Laws differ by country and state, and the illicit market is full of mislabeled product. Check dancesafe.org and test any substance before use.

Myth or fact?

You made it ✦

Come back anytime to revisit. Knowing what you're actually taking - and how much - keeps you and the people around you safer.

Finish →

Course complete

You finished 2C-B 101. Knowing more keeps you and your people safer.

Sources

dancesafe.org · psychonautwiki.org · erowid.org
Shulgin, PiHKAL · Gonzalez et al. 2015 · Mallaroni et al. 2023
Papaseit et al. 2018 · pubmed.ncbi.nlm.nih.gov

Portal is an IRS-recognized 501(c)(3) nonprofit, and this is harm-reduction education central to our mission - not medical or legal advice, and never an endorsement to use any drug. We do not encourage or promote using any substance. 2C-B is illegal in most places, and what's sold as "2C-B" is often something else. In an emergency, call 911. Need support during or after an experience? The Fireside Project psychedelic peer-support line: 62-FIRESIDE (623-473-7433), free and confidential.

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